Isesengura ry'impamvu y'urupfu rukabije mu Kubiba

Mubuvuzi, indwara zikunze gutera urupfu rukabije mu mbuto zirimo umuriro w’ingurube zo muri Afurika, umuriro w’ingurube wa kera, ibisebe bikabije byo mu gifu (perforation), septique ya bacteri ikaze (nka B yo mu bwoko bwa B Clostridium novyi, erysipelas), kandi ikarenga imipaka. uburozi mu biryo. Byongeye kandi, kwandura kwinkari mu mbuto zatewe na Streptococcus suis nazo zishobora gutera urupfu rukabije.

Ururenda ni urugingo rukomeye rw’umubiri rufite uruhare mu gusubiza ubudahangarwa no kuyungurura amaraso, rukaba nk'urugamba rukomeye mu kurwanya umubiri indwara ziterwa na virusi. Kubwibyo, mugihe cyanduye sisitemu yanduye, ururenda rwerekana reaction zikomeye. Indwara ya splenitis ikaze, aho ururenda rwikubye inshuro nyinshi kurenza ibisanzwe, rushobora guterwa n'indwara nk'umuriro w'ingurube zo muri Afurika, umuriro w'ingurube wa kera, hamwe na septique ya bacteri ikaze (ishobora kuba irimo bagiteri zitandukanye nka streptococci na Clostridium novyi). Dushingiye ku mpinduka zikomeye z’indwara zifata ururenda, icyo twibandaho ni umuriro w’ingurube zo muri Afurika, umuriro w’ingurube wa kera, na septique ya bagiteri mu ngurube. Indwara ya porcine circovirus na virusi ya syndrome ya porcine yimyororokere nubuhumekero mubisanzwe ntabwo itanga impinduka zikomeye zemeza indwara zimpyiko; circovirus ikunze gutera granulomatous splenitis, igaragara gusa munsi ya microscope.

Igisebe cyo mu gifu bivuga indigestion ikaze ndetse no kuva amaraso mu gifu biganisha ku isuri ya tissue yaho, necrosis, cyangwa autodigestion ya mucosa gastrica, bikaviramo ibikomere bikabije cyangwa no gutobora gastric. Mbere y’umuriro w’ingurube zo muri Afurika, ibisebe byo mu gifu nibyo byateje impfu nyinshi mu mbuto z’Abashinwa. Birashimishije kubona ibisebe byo mu gifu hafi ya esofagusi cyangwa pylorus bifite akamaro ko gusuzuma, mu gihe ibisebe byo mu bindi bice by'igifu bidafite. Kuri iki gishushanyo, nta bisebe bikomeretsa bigaragara mu gifu, bityo ibisebe byo mu gifu birashobora kuvaho nk'intandaro y'urupfu rukabije mu mbuto.

Ishusho yo hepfo yibumoso yerekana umwijima. Umwijima ugaragara neza, wuzuyemo imyenge mito itandukanye isa n'ifuro. Indwara yumwijima yibiranga iranga anatomique iterwa no kwandura Clostridium novyi mu ngurube. Biragoye gusesengura uburyo Clostridium novyi retrogrades kugirango igere ku mwijima no kwangiza umwijima.

Binyuze mu binyabuzima bya molekuline, turashobora gukuramo umuriro w’ingurube nyafurika hamwe n’ingurube ya kera. Indwara za bagiteri zishobora gutera urupfu rukabije mu mbuto zirimo erysipelas, Actinobacillus pleuropneumoniae, na Clostridium novyi. Nyamara, indwara za bagiteri nazo zigaragaza ahantu hatandukanye ho gutera no kuranga ibyangiritse; nk'urugero, Actinobacillus pleuropneumoniae ntabwo itera splenite ikaze gusa ahubwo icy'ingenzi ni nekrotizing pemumoniya. Streptococcus suis itera ibikomere byinshi byuruhu. Indwara ikabije yumwijima yerekana icyerekezo cyihariye; umwijima mwinshi mubisanzwe biranga igikomere cya Clostridium novyi mu ngurube. Ubundi isuzuma rya microscopique ryemeza ko Clostridium novyi ari yo nyirabayazana w'urupfu rukabije mu mbuto. Ibisubizo biranga umuco wa bagiteri byemeza Clostridium novyi.

Muri iki gihe, uburyo butandukanye burashobora gukoreshwa muburyo bworoshye, nko gusiga umwijima. Mubisanzwe, nta bagiteri igomba kugaragara mu mwijima. Iyo bagiteri zimaze kugaragara, hamwe no gukomeretsa kwa anatomique nkimpinduka zimeze nkumwijima zimeze, zishobora gufatwa nkindwara zifata. Ubundi bugenzuzi bushobora gukorwa binyuze muri HE kwanduza umwijima, bikagaragaza bagiteri nyinshi zimeze nkinkoni. Umuco wa bagiteri ntabwo ukenewe kuko Clostridium novyi ni imwe muri bagiteri igoye kumuco.

Gusobanukirwa ibiranga ibyangiritse nibibanza bya buri ndwara ni ngombwa. Kurugero, virusi ya pcine epidemic diarrhea yibasira cyane cyane selile epithelial selile y amara mato, kandi ibyangiritse mubindi bice nkibihaha, umutima, cyangwa umwijima ntabwo biri murwego rwayo. Igitero cya bagiteri giterwa cyane n'inzira zihariye; kurugero, Clostridium tetani irashobora kwanduza gusa ibikomere byanduye cyane hamwe na nerotic cyangwa impinduka zidasanzwe, mugihe izindi nzira zidatera kwandura. Indwara ya Actinobacillus pleuropneumoniae ishobora kugaragara cyane mu bworozi bw'ingurube hamwe na grippe na pseudo-rabies, kubera ko izo virusi zangiza byoroshye ingirabuzimafatizo ya tracheal epithelia, bigatuma byoroha Actinobacillus pleuropneumoniae kwinjira no gutura muri alveoli. Abaveterineri bagomba gusobanukirwa ibiranga kwangirika kwingingo za buri ndwara hanyuma bagahuza uburyo bwo gupima laboratoire nka biologiya ya molekuline na microbiologiya kugirango basuzume neza indwara.